Compounded Chlorambucil (Leukeran)
This medication is used in both humans and animals. It is important to note that the strength given to humans is often not suitable for animals. Most often prescriptions for animals require a compounded medication. Chlorambucil is a chemotherapy (anticancer) and immunosuppressive drug. It is used to treat a variety of cancers in animals as well as some conditions associated with overactive immune systems. It often takes several days until any benefits of the medication are seen and takes several weeks of consistent dosing until the medications full effects is reached. Chlorambucil does require a prescription from your veterinarian in order to be dispensed. You and your veterinarian should discuss if this is the best option for your pet.
Chlorambucil is given orally and can be compounded into the desired strength and flavor that best suits your pet. We compound this medication into suspensions and capsules. It is important to note that the strength given to humans is often not suitable for animals. Chlorambucil is best given with food. This medication is considered a hazardous drug and may be harmful to individuals that touch the medication if it is not prescribed to them. Therefore, gloves should be worn while administering the medication to your animal. In addition, pregnant women should use caution when handling this medication as it may contribute to a higher risk for birth defects. Any bodily fluids (urine, feces, vomit etc.) from an animal on this medication should also be handled using gloves. Chlorambucil should be given as instructed on your prescription. If you miss a dose do not double up on the medication. Wait until the next dose is due and follow the normal dosing schedule as directed.
The most common side effects in animals while taking chlorambucil is loss of hair and GI upset. Overdoses of this medication can be serious. If you suspect an overdose, contact your veterinarian or poison control.