Compounded Cisapride (Propulsid) For Dogs, Cats, and Horses

Cisapride is a medication used in animals only to help stimulate food through the stomach and intestines. In small animals, it can be useful to treat esophageal reflux or esophagitis. Cisapride has also been shown to help treat megacolon and constipation in feline patients. Cisapride is often given before surgical procedures due to these mechanisms. How long your pet stays on Cisapride will depend on the condition of each animal and should be discussed with the veterinarian. This medication is not used in humans. This medication should take effect within 1-2 hours and the clinical signs of improvement in your animal’s health should also be fairly rapid. Your veterinarian may require follow up tests and visits to ensure the medication is working properly. Cisapride does require a prescription from your veterinarian in order to be dispensed. You and your veterinarian should discuss of this is the best option for your pet.

Cisapride is given orally and must be compounded as it is no longer commercially available. Trained staff at Dalcoma Specialty Pharmacy can compound this medication into the desired strength and flavor that best suits your pet. We compound this medication into suspension and capsules. This medication may be given with or without food. If your pet vomits after trying the medication on an empty stomach, the next dose should be given with food to help reduce GI upset. If you miss a dose do not double up on the medication. Wait until the next dose is due and follow the normal dosing schedule as directed.

Common side effects of Cisapride are often minimal and may include vomiting, diarrhea, and abdominal discomfort. If your animal experiences weakness, stumbling, excessive salivation (drooling), muscle twitching, seizures, or high body temperature please contact your veterinarian immediately as these symptoms may indicate a serious reaction. If you suspect an overdose, contact your veterinarian or poison control.