Compounded Diethylstilbestrol (DES) For Dogs

DES is a synthetic estrogen that is used in animals. Diethylstilbestrol can be used to treat urinary incontinence in some female dogs and may also be used to induce heat. It is rarely used in cats due to the side effects seen in felines. This medication should help your animal improve within 1 to 2 days. Diethylstilbestrol (DES) does require a prescription from your veterinarian in order to be dispensed. You and your veterinarian should discuss if this is the best option for your pet.

DES is given orally and can be compounded into the desired strength and flavor that best suits your pet. We compound this medication into capsules. DES may be given with or without food. If your animal vomits when the dose is given on an empty stomach, you may try to give the medication with a small snack to combat this side effect. This medication is considered a hazardous drug and may be harmful to individuals that touch the medication if it is not prescribed to them. Therefore, gloves should be worn while administering the medication to your animal. In addition, pregnant women should use caution when handling this medication as it may contribute to a higher risk for birth defects. Diethylstilbestrol (DES) should be given as instructed on your prescription. If you miss a dose do not double up on the medication. Wait until the next dose is due and follow the normal dosing schedule as directed.

The most common side effect of this medication is vaginal spotting in intact females. Feline patients are more susceptible to more serious side effects. If your animal starts experiencing a loss of appetite or any bleeding, contact your veterinarian as these may be signs of more serious issues. Overdoses of this medication can be serious. If you suspect an overdose, contact your veterinarian or poison control.