Compounded Lomustine (CeeNU, Gleostine) For Dogs and Cats

Lomustine is an anticancer agent that is used in chemotherapy treatment. This medication should start having effects within 1-2 days after staring the treatment regimen however, full effects of the medication may not be seen for several weeks. Often side effects of the medication may occur right away. Lomustine does require a prescription from your veterinarian in order to be dispensed. You and your veterinarian should discuss if this is the best option for your pet.

Lomustine is given orally and can be compounded into the desired strength and flavor that best suits your pet. We compound this medication into suspensions and capsules. It is important to note that the strength given to humans is often not suitable for animals. Lomustine is best given with food. This medication is considered a hazardous drug and may be harmful to individuals that touch the medication if it is not prescribed to them. Therefore, gloves should be worn while administering the medication to your animal. In addition, pregnant women should use caution when handling this medication as it may contribute to a higher risk for birth defects. Lomustine should be given as instructed on your prescription. If you miss a dose do not double up on the medication. Wait until the next dose is due and follow the normal dosing schedule as directed.

The most common side effects of this medication are bone marrow suppression, vomiting, diarrhea, ulcers and other GI upset. In canine patients, hair loss or changes may be observed. Liver damage and lug damage may also occur. If your animal starts coughing or having trouble breathing, contact your veterinarian as these may be signs of more serious issues. Overdoses of this medication can be serious. If you suspect an overdose, contact your veterinarian or poison control.